Hovav Nechushtan Selected Research

Pharmaceutical Preparations

1/2022	Ex vivo organotypic cultures for synergistic therapy prioritization identify patient-specific responses to combined MEK and Src inhibition in colorectal cancer.
11/2016	Cabozantinib for metastatic breast carcinoma: results of a phase II placebo-controlled randomized discontinuation study.
4/2015	A phase IIb trial assessing the addition of disulfiram to chemotherapy for the treatment of metastatic non-small cell lung cancer.
11/2008	Mast cells and cancer--no longer just basic science.
8/2002	[Tamoxifen and breast cancer].

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Hovav Nechushtan Research Topics

Disease

27	Neoplasms (Cancer) 01/2022 - 08/2002
10	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 04/2022 - 02/2012
8	Lung Neoplasms (Lung Cancer) 01/2021 - 03/2013
6	Breast Neoplasms (Breast Cancer) 01/2021 - 08/2002
4	Neoplasm Metastasis (Metastasis) 01/2017 - 08/2014
3	Brain Neoplasms (Brain Tumor) 01/2022 - 01/2020
2	Adenocarcinoma of Lung 01/2022 - 02/2012
2	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 02/2012
2	Sarcoma (Soft Tissue Sarcoma) 01/2021 - 08/2002
2	Carcinoma (Carcinomatosis) 01/2017 - 08/2002
2	Renal Cell Carcinoma (Grawitz Tumor) 04/2016 - 08/2010
2	Cardiomegaly (Heart Hypertrophy) 09/2015 - 10/2006
2	B-Cell Lymphoma (Lymphoma, B Cell) 01/2010 - 11/2009
2	Body Weight (Weight, Body) 10/2006 - 08/2002
1	Dermatomyositis (Dermatopolymyositis) 09/2021
1	Disease Progression 01/2020
1	Microsatellite Instability 01/2018
1	Neuroendocrine Tumors (Neuroendocrine Tumor) 01/2017
1	Respiratory Insufficiency (Respiratory Failure) 11/2016
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 02/2016
1	Heart Failure 09/2015
1	Triple Negative Breast Neoplasms 08/2014
1	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2010
1	Lymphopenia (Lymphocytopenia) 05/2008
1	Lewis Lung Carcinoma 10/2007

Drug/Important Bio-Agent (IBA)

5	Pharmaceutical PreparationsIBA 01/2022 - 08/2002
4	Tyrosine Kinase InhibitorsIBA 04/2022 - 05/2010
4	PlatinumIBA 01/2022 - 01/2017
3	ErbB Receptors (EGF Receptor)IBA 04/2022 - 01/2020
3	osimertinibIBA 01/2022 - 01/2020
3	pembrolizumabIBA 01/2022 - 01/2017
3	LigandsIBA 01/2021 - 09/2015
3	Tyrosine (L-Tyrosine)FDA Link 01/2021 - 04/2013
3	Phosphotransferases (Kinase)IBA 01/2021 - 11/2008
3	thymidine kinase 1IBA 04/2016 - 08/2010
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2022 - 01/2021
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2022 - 01/2019
2	Drug CombinationsIBA 01/2022 - 01/2021
2	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2021
2	Serine (L-Serine)FDA Link 11/2018 - 09/2017
2	Lysine-tRNA LigaseIBA 11/2018 - 09/2017
2	Microphthalmia-Associated Transcription FactorIBA 09/2015 - 09/2002
2	Cytotoxins (Cytolysins)IBA 10/2014 - 05/2008
2	Interleukin-4 (Interleukin 4)IBA 11/2009 - 04/2005
2	OvalbuminIBA 05/2008 - 10/2007
1	AutoantibodiesIBA 09/2021
1	Alanine Transaminase (SGPT)IBA 01/2021
1	human ERBB2 proteinIBA 01/2021
1	CrizotinibIBA 01/2021
1	Anaplastic Lymphoma KinaseIBA 01/2021
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2021
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2021
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2021
1	Gefitinib (Iressa)FDA Link 01/2020
1	Erlotinib Hydrochloride (CP 358,774)FDA Link 01/2020
1	Biomarkers (Surrogate Marker)IBA 11/2019
1	Platinum Compounds (Compounds, Platinum)IBA 11/2019
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 12/2018
1	B7-H1 AntigenIBA 01/2018
1	1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acidIBA 01/2017
1	cabozantinibIBA 11/2016
1	pro-gastrin-releasing peptide (31-98)IBA 02/2016
1	Peptides (Polypeptides)IBA 02/2016
1	big gastrinIBA 02/2016
1	NivolumabIBA 01/2016
1	MicroRNAs (MicroRNA)IBA 06/2015
1	Disulfiram (Antabuse)FDA Link 04/2015
1	Cisplatin (Platino)FDA LinkGeneric 04/2015
1	Vinorelbine (Navelbine)FDA LinkGeneric 04/2015
1	Growth Factor ReceptorsIBA 10/2014
1	Cetuximab (Erbitux)FDA Link 08/2014
1	taxaneIBA 08/2014
1	Taxoids (Taxanes)IBA 08/2014
1	Formaldehyde (Formol)FDA Link 02/2012
1	ParaffinIBA 02/2012
1	EnzymesIBA 08/2010
1	Pyruvate KinaseIBA 08/2010
1	masitinibIBA 05/2010
1	pazopanib FDA Link 05/2010
1	Imatinib Mesylate (Gleevec)FDA Link 05/2010
1	Interleukin-21 ReceptorsIBA 01/2010
1	interleukin-21 (interleukin 21)IBA 01/2010
1	DNA (Deoxyribonucleic Acid)IBA 02/2009
1	Interferon-gamma (Interferon, gamma)IBA 05/2008
1	CytokinesIBA 05/2008
1	AntigensIBA 10/2007
1	Bromodeoxyuridine (BrdU)IBA 10/2007
1	Atrial Natriuretic Factor (ANF)IBA 10/2006
1	Transcription Factors (Transcription Factor)IBA 10/2006
1	Adrenergic Agents (Adrenergic Drugs)IBA 10/2006

Therapy/Procedure

13	Therapeutics 01/2022 - 05/2008
9	Drug Therapy (Chemotherapy) 01/2022 - 11/2009
2	Radiotherapy 01/2021 - 10/2014
2	Nephrectomy 04/2016 - 08/2010
1	Time-to-Treatment 01/2021
1	Precision Medicine 01/2021
1	Immunotherapy 01/2021
1	Radiofrequency Ablation 04/2016
1	Adjuvant Chemotherapy 04/2013
1	Injections 05/2008